Beyond Hot Flushes: How Your Gut Microbiome Shapes Menopause and Where Clarity Fits In

When we think about menopause, we often focus on hormones—particularly oestrogen. But research suggests there may be another important player: the gut microbiome. 

This community of trillions of microbes in your digestive system doesn’t just help you digest food—it also plays a role in influencing your metabolism, immune system, and even your mood. And during menopause, changes in the gut microbiome may be one factor that contributes to how symptoms are experienced. 

Let’s explore what current research suggests about the relationship between gut health and menopause and how Clarity, a daily food supplement, has been designed to support women during this stage of life. 

1. The Estrobolome—What Is It and Why Does It Matter? 

Some gut bacteria are thought to support the breakdown and recycling of oestrogens through an enzyme called β-glucuronidase. This microbial activity—sometimes referred to as the “estrobolome” may influence oestrogen metabolism. 

As we age, especially after midlife, the diversity of gut bacteria may change. These shifts have been linked in emerging research to changes in hormone metabolism, inflammation, and symptoms such as hot flushes, mood variability, or digestive changes. It’s important to note that this area of science is still developing. 

2. Probiotics and the Gut–Menopause Connection 

Probiotics are live microorganisms that, when taken in adequate amounts, may confer a benefit to the host. While they’re widely known for digestive support, certain strains are being explored in research for their potential role in other aspects of health, including immune function, mood, and metabolic balance. 

In the context of menopause, some studies have looked at whether specific probiotic strains may be able to influence: 

Pathway	Area of Research
Hormone metabolism	Supporting oestrogen processing
Gut–brain axis	Interactions with mood and sleep
Immune signalling	Potential to reduce low-grade inflammation

These potential benefits vary from person to person, and no probiotic can prevent or treat menopause-related conditions. 

3. About Clarity: A Food Supplement for Midlife Women 

Clarity is a daily food supplement formulated for women in midlife. It contains two probiotic strains, Bifidobacterium longum and Lactobacillus acidophilus (YT1), selected based on their inclusion in emerging research on psychological wellbeing, gut health, and women’s quality of life. 

Strain	Quantity	Focus of Research*
Bifidobacterium longum	50 mg	Psychological wellbeing, stress, sleep
Lactobacillus acidophilus YT1	20 mg	Menopause-related quality of life

Studies referenced involved specific populations and outcomes and may not apply to everyone. Food supplements should not be used as a substitute for a varied diet and healthy lifestyle. 

4. Lifestyle Tips to Support Your Gut in Midlife 

Whether or not you take a probiotic supplement, there are daily habits that may help to support your gut health: 

• Consistency matters – Take supplements at the same time each day, preferably with food. 

• Feed your microbes – Add prebiotic fibres like flaxseeds, oats, or inulin. 

• Choose colourful foods – Polyphenol-rich foods like berries, walnuts, and pomegranate may support microbial diversity. 

• Be mindful with medicines – Space antibiotics or NSAIDs at least four hours apart from probiotics. 

• Track changes – Use a symptom tracker or journal to note any changes in how you feel. 

5. Frequently Asked Questions 

Q: How long until I might notice changes? A: Everyone is different. Some people report changes within a few weeks, while for others it may take longer. Gut microbiome shifts occur gradually over time. 

Q: Can I take Clarity with HRT? A: Clarity is a food supplement and not known to interact with hormone replacement therapy. However, always consult a healthcare professional before adding new supplements, especially if you have a medical condition or take prescription medication. 

Q: Is it normal to feel bloated when starting probiotics? A: Some people experience mild digestive changes when introducing probiotics. This is usually temporary but consult your GP or pharmacist if symptoms persist. 

Menopause is a complex transition involving not just hormonal changes, but also shifts in other body systems including the gut. While probiotics are not a treatment for menopause symptoms, there is growing interest in their potential to support general wellbeing, digestive comfort, and mood regulation. 

Clarity was formulated to support gut health in midlife, with two carefully selected probiotic strains. When used alongside a balanced diet and lifestyle, it may be a helpful addition to your self-care routine during menopause. 

This article is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Food supplements should not be used as a substitute for a varied diet and healthy lifestyle. Always seek advice from a healthcare provider before starting any new supplement.